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What does the next phase of medication distribution look like?

By Dennis Tribble posted 05-23-2025 12:58

  

Today I was cleaning out my hard drive and ran across a draft document that never seemed to have gone anywhere entitled "Rethinking Medication Distribution in the Acute Care Setting". It is probably a couple of years old now, but I think it raises some questions that we need to answer as a profession. My interest was piqued by the article by Flynn et al entitled "The Autonomous Pharmacy"1, which did an excellent job of describing a 50,000 foot view of the problem but lacked details, as a vision statement should.

It also reminded me of a classic video of a lecture by Russ Ackoff (that I recommend to your viewing) wherein he describes the process by which Bell Labs moved telephony from the rotary dial telephone to most of what we enjoy (and rely on!) in modern communications. A key point in this tale involves their  realizing that they had been incrementally improving on the same technology (the rotary dial telephone) for 50 years! It was time to throw it all away and start over.

I have had the privilege of knowing and working with a number of folk who were involved with our current acute care medication distribution technologies and realized that the oldest of those relationships goes back about 30 years. In those 30 years, we have been incrementally improving (maybe) those technologies but have introduced very little in the way of substantive or disruptive improvement.

This, in turn, caused me to look back on my over 50 years of practice experience and to assess how acute care medication distribution has changed. I experienced complete floor stock distribution, individual inpatient prescription (3-day supply labeled for the patient), unit-dose drug distribution (exchange carts) and, finally, automated dispensing cabinets (ADC). 

Each of those steps reduced the supply of medications on the floor, presumably improved the safety of the medication administration process, and increased the nursing staff's dependency on pharmacy operations. 

Each was expected to reduce the time pharmacy spent running medications to the patient care areas; a benefit that was not realized. It turned out that managing all those disparate inventories required (and still requires) a lot of human effort.

So, in the last 30 years, we have operated on a hybrid system in which some medications are delivered by ADC and some are not and have made few, if any,  substantive changes in the way we deliver medications to patients. 

Maybe it's time to take a page out of the Bell Labs playbook, and think about what an ideal distribution system might look like given the technologies that we have or are likely to have in the twenty-first century. If we were to start that process the way Ackoff describes, we would first start by enumerating problems in the current system we have to solve, and then set about solving them.

  • Nursing workflow is hectic2,3,4,5,6. When our distribution systems interrupt medication administration to source needed medications, it becomes even more so. When a nurse has to run back and forth to an ADC, their risk of being interrupted escalates.
  • Research I have done using ADC transactional data indicates has led to the development of an analytical model that identifies trips from the pharmacy to the patient care areas.7 It is by no means perfect, but irrespective of how it is configured or the relative size of the institution, the model shows that the most frequent trips involve few medications at few ADCs. This means that pharmacy is spending a lot of time running small amounts of medication up to the patient care areas.

One way we could solve both of these issues is to have a distribution system that delivers scheduled (and, perhaps PRN) medications just-in-time. The cost to do this with humans would be prohibitive, but, with advances that are occurring within the robotic space a number of things might be practical. Imagine a nurse being able to walk into a patient room, assess the patient condition, acquire the medications without having to leave the room (and ger interrupted many times) , administer and document the administration of those medications, assess the impact of the medications, and move to the next patient. I agree that there is a lot of magical thinking included in that description, but imagine how much more effective medication administration could be.

What do you think?

Dennis A. Tribble, PharmD, FASHP

Retired

Ormond Beach, FL

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1 Flynn A et al The Autonomous Pharmacy Amer J Health-Syst Pharm 78(7):636-645 April 1, 2021

2 Keohane, C et al Quantifying Nursing Workflow in Medication Administration JONA 38(1);19-26 January 2008 

3 Garrett, S and Craig J Medication Administration and the Complexity of Nursing Workflow Clemson University(2009)

4 Cain C, Haque S Chapter 31 organizational Workflow and Its Impact on Work Quality Patient Safety and Quality: An Evidence-Based Handbook for Nurses Hughes, RG editor published by AHRQ, April 2008

5 Cornell P et al Transforming Nursing Workflow, Part 1: The Chaotic Nature of Nurse Activities JONA 40(9):366-373 September 2010

6 Cornell P et al Transforming Nursing Workflow, Part2: The Impact of Technology on Nurse Activities JONA 40(10):432-439 October 2010

7 Tribble, D Trips Model, patent pending - Application number WO2022271384 A1

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05-28-2025 12:24

Zarni,

Thank you for your thoughtful comments.

My general observation is that practice evolves and roles evolve with those changes. One's role is challenged by technological change only if we refuse to evolve ourselves with those changes.

These changes aren't new. I am old enough to recall when all of our distribution and charging functions were on paper, and we had billing technicians to submitted charge requisitions to finance. Then we put in a computer system that captured all that data automatically and submitted the date to finance automatically every day. Those technicians had to learn new roles, of which there were many, including maintaining the computer system!!

So, as you think more broadly of how AI and robotics might displace current functions technicians perform, think about the opportunities they might create for pharmacy technicians.

We know, for example, that Pharmacy Technicians are excellent at taking medication histories as part of an ongoing Medication Reconciliation program. This has been limited to some extent by the fact that other, more mundane roles command so much of our pharmacy technician time, especially now that pharmacy technicians are in shorter supply than pharmacists. If those tasks were to become automated, being more involved in medication reconciliation might be a real opportunity (which, by the way, has a known and very real ROI).

We know that follow-up calls to at-risk patients regarding their medication supplies and their reaction to post-discharge medications have a real impact on reducing 30-day readmissions. Does a pharmacist have to make all those calls, or should they be involved only when there are truly clinical issues to resolve (as opposed to drug access or coverage issues)?

Any new technology requires management. AI and robotics are no different. Being involved in those pursuits represents yet another opportunity.

So I encourage you to see technology change not as a hazard, but as an opportunity.

05-25-2025 08:29

"We Know What Has Been Going on with Medication Distribution" 
A Sequel to "What Does the Next Phase of Medication Distribution Look Like? 
Dear Mr. Tribble,
 
Thank you for your insightful article, "What Does the Next Phase of Medication Distribution Look Like?". Please let me have this honor as a sequel to continue your storyline, from a Certified Pharmacy Technician (CPhT) navigating the evolving healthcare landscape.
 
Our medication distribution systems are getting more developed, causing drama in the industry. Over the past three decades, we've transitioned from floor stock systems to unit-dose carts and automated dispensing cabinets (ADCs). While these advancements have improved certain aspects of our workflow, they haven't fully addressed persistent challenges such as labor-intensive inventory management, frequent disruptions to nursing workflows in clinics, or chaos in retail pharmacy settings, especially in the Pandemic era.
 
Embracing emerging technologies, particularly robotics and automation, could pave the way for a just-in-time delivery system. For example, this clinical model would enable nurses to access medications directly at the point of care, reducing interruptions and enhancing patient safety. Nurses have been given and regulated by layers of tasks, and so do we. However, as we welcome this idea to consider the solutions and innovations like checking robotics and automation, we must acknowledge the current challenges within our profession.
People still rely on picking up their medications from the local pharmacies in their neighborhood. Unfortunately, those pharmacy closures nationwide and economic pressures have made it increasingly difficult for the majority of experienced technicians and some pharmacists to secure stable employment. Moreover, while the demand for pharmacy technicians is projected to grow, the current economic climate and industry consolidation make it difficult for professionals to find opportunities that match their skill levels. Are we being forgotten?
 
Despite these challenges, we still struggle to remain committed to our professions to provide patients with the best quality care. We, CPhTs, could probably be the first to be killed when AI begins to take over. We hope that by adapting to the evolving healthcare environment, such as the ones with AI, advocating for the essential role of pharmacy technicians, and having equal access to continuous education with PharmDs, we will still make meaningful contributions to patient health and well-being.
 
Your vision especially challenges CPhTs to think beyond incremental improvements and consider how we can leverage this newest innovative AI technology to revolutionize medication distribution. Doing so enhances our profession and contributes to better patient outcomes and a more resilient healthcare system with our PharmDs.
 
Thank you for sparking this critical conversation.
 
Sincerely,
 
Zarni Htay, CPhT
Certified Pharmacy Technician, San Francisco Bay Area, CA
 
1. Tribble, Dennis. "What Does the Next Phase of Medication Distribution Look Like?" *ASHP Connect*, 17 Apr. 2025.
 
2. "The State of the Pharmacy Technician Workforce." *Pharmacy Technician Certification Board*, 2025. 
 
3. "APhA is Addressing Pharmacy Technician Workforce Needs." *American Pharmacists Association*, 2025. 
 
4. "Pharmacy Tech Job Outlook 2025." *ShiftPosts*, 2025. 
 
5. "Combating the Post-Pandemic Pharmacy Workforce Shortage." *Pharmacy Times*, 2025.