Hi ASHP Community,
Anyone willing to share how you are diluting IV phenytoin doses in order to have a final concentration of no less than 5mg/ml?
Thanks so much! Gail
Gail M. Sanchez, PharmD, BCPS, DPLA
Cambridge Health Alliance
For doses <1 gram it should be diluted in 100ml NS. For doses >1gram should be diluted in 250ml NS. That should keep the concentration within the 5mg/ml range.
500ml/100ml NS
250mg/50ml NS
125mg/25ml NS